{"id":5662,"date":"2023-03-02T16:06:55","date_gmt":"2023-03-02T16:06:55","guid":{"rendered":"http:\/\/dti.developallin.com\/tejidos-para-investigacion\/"},"modified":"2026-04-15T10:21:34","modified_gmt":"2026-04-15T10:21:34","slug":"human-biological-samples","status":"publish","type":"page","link":"https:\/\/dtifoundation.com\/es\/investigacion-y-desarrollo\/human-biological-samples\/","title":{"rendered":"Human Biological Samples (HBS)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=\u00bb0&#8243; override_padding=\u00bbyes\u00bb h_padding=\u00bb2&#8243; top_padding=\u00bb3&#8243; bottom_padding=\u00bb3&#8243; overlay_alpha=\u00bb50&#8243; gutter_size=\u00bb3&#8243; column_width_percent=\u00bb100&#8243; shift_y=\u00bb0&#8243; z_index=\u00bb0&#8243; uncode_shortcode_id=\u00bb369816&#8243;][vc_column width=\u00bb2\/3&#8243;][vc_custom_heading text_color=\u00bbcolor-red-tpm-dti\u00bb heading_semantic=\u00bbdiv\u00bb text_size=\u00bbh5&#8243; text_weight=\u00bb600&#8243; uncode_shortcode_id=\u00bb580817&#8243; text_color_type=\u00bbuncode-palette\u00bb]Desarrollo de Investigaci\u00f3n[\/vc_custom_heading][vc_custom_heading text_color=\u00bbcolor-jevc\u00bb text_transform=\u00bbuppercase\u00bb uncode_shortcode_id=\u00bb371731&#8243; text_color_type=\u00bbuncode-palette\u00bb]Human Biological Samples[\/vc_custom_heading][vc_column_text uncode_shortcode_id=\u00bb747206&#8243;]<\/p>\n<p style=\"text-align: justify;\">El departamento de <strong>Desarrollo de Investigaci\u00f3n<\/strong> de la Fundaci\u00f3n DTI apoya a grupos de investigaci\u00f3n de primer nivel en el desarrollo de proyectos de investigaci\u00f3n b\u00e1sica y precl\u00ednica en el campo de las Terapias Avanzadas.<br \/>\nLos proyectos impulsados por DTI se centran en desarrollar herramientas humanas predictivas <em>in vitro<\/em> para lograr varios objetivos:<\/p>\n<ul style=\"text-align: justify;\">\n<li><strong>Anticipar<\/strong> posibles efectos adversos, ineficaces o t\u00f3xicos derivados de la acci\u00f3n de compuestos inmunomoduladores en pacientes con c\u00e1ncer.<\/li>\n<li><strong>Identificar<\/strong> nuevas dianas terap\u00e9uticas y\/o biomarcadores que puedan mejorar el pron\u00f3stico de los pacientes.<\/li>\n<li><strong>Dise\u00f1ar y validar<\/strong> modelos de organoides mediante una caracterizaci\u00f3n exhaustiva, que incluya pruebas de f\u00e1rmacos y an\u00e1lisis \u00f3micos detallados<br \/>\n(gen\u00f3mica, transcript\u00f3mica, prote\u00f3mica y epigen\u00f3mica) tanto de organoides como de tejidos, evaluando su similitud molecular y celular con los tejidos originales.<\/li>\n<li><strong>Desarrollar y optimizar<\/strong> herramientas avanzadas para analizar el impacto de diversos componentes en las estructuras de los organoides, con el objetivo de comprender m\u00e1s profundamente sus mecanismos moleculares.<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">El desarrollo de terapias avanzadas aporta importantes beneficios m\u00e9dicos y sociales, con el potencial de transformar los sistemas sanitarios y mejorar la calidad de vida en \u00e1reas como:<\/p>\n<ul>\n<li style=\"text-align: justify;\"><strong>Tratamiento de enfermedades antes incurables:<\/strong> Permiten abordar afecciones raras, gen\u00e9ticas o degenerativas sin opciones terap\u00e9uticas efectivas, como la distrofia muscular, la ELA o ciertos tipos de c\u00e1ncer.<\/li>\n<li style=\"text-align: justify;\"><strong>Terapias personalizadas:<\/strong> Ofrecen tratamientos adaptados a las caracter\u00edsticas gen\u00e9ticas y biol\u00f3gicas de cada paciente, mejorando la eficacia y reduciendo efectos secundarios.<\/li>\n<li style=\"text-align: justify;\"><strong>Regeneraci\u00f3n y reparaci\u00f3n de tejidos y \u00f3rganos:<\/strong> Restauran funciones corporales deterioradas, mejorando significativamente la salud de pacientes con fallo org\u00e1nico o lesiones.<\/li>\n<li style=\"text-align: justify;\"><strong>Reducci\u00f3n de la dependencia de tratamientos cr\u00f3nicos:<\/strong> Muchas terapias avanzadas proporcionan curas definitivas o soluciones de larga duraci\u00f3n, disminuyendo la necesidad de medicaci\u00f3n constante.<\/li>\n<li style=\"text-align: justify;\"><strong>Reducci\u00f3n del uso de modelos animales:<\/strong> Estas t\u00e9cnicas permiten crear modelos humanos <em>in vitro<\/em> precisos, evitando las limitaciones de la traslaci\u00f3n animal-humano y promoviendo una investigaci\u00f3n biom\u00e9dica m\u00e1s \u00e9tica y sostenible.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_tabs align=\u00bbleft\u00bb el_id=\u00bbtabs-rd\u00bb][vc_tab gutter_size=\u00bb2&#8243; column_padding=\u00bb2&#8243; title=\u00bbNuetros valores\u00bb tab_id=\u00bb1683805219-1-1&#8243;][uncode_list icon=\u00bbfa fa-chevron-right2&#8243; icon_color=\u00bbcolor-red-tpm-dti\u00bb uncode_shortcode_id=\u00bb370697&#8243; icon_color_type=\u00bbuncode-palette\u00bb]<\/p>\n<ul>\n<li><strong>Multidisciplinary<\/strong> <strong>approach<\/strong>: Coordinated teamwork with professionals from diverse fields.<\/li>\n<li><strong>Adaptability<\/strong>: Flexible methodology tailored to each project&#8217;s context and needs.<\/li>\n<li><strong>Commitment<\/strong>: Active involvement of the team throughout all phases of the process.<\/li>\n<li><strong>Availability<\/strong>: Continuous support and responsiveness to ensure project success.<\/li>\n<li><strong>Rigorous methodology:<\/strong> Strict application of protocols and quality standards at every step.<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_tab][vc_tab gutter_size=\u00bb2&#8243; column_padding=\u00bb2&#8243; title=\u00bbPor qu\u00e9 DTI\u00bb tab_id=\u00bb1683805219-2-37&#8243;][vc_column_text uncode_shortcode_id=\u00bb413034&#8243;]Para garantizar que este proceso esencial se realice con \u00e9xito, la Fundaci\u00f3n DTI brinda apoyo con:[\/vc_column_text][uncode_list icon=\u00bbfa fa-chevron-right2&#8243; icon_color=\u00bbcolor-red-tpm-dti\u00bb uncode_shortcode_id=\u00bb270589&#8243; icon_color_type=\u00bbuncode-palette\u00bb]<\/p>\n<ul>\n<li>Customized project design:\n<ul>\n<li>By linking biobanks, processing centers, and laboratories<\/li>\n<\/ul>\n<\/li>\n<li>Specialists obtaining fresh samples:\n<ul>\n<li>Through management of minimum cold ischemia for any type of tissue<\/li>\n<li>Shipping times of less than 24 hours in Europe<\/li>\n<\/ul>\n<\/li>\n<li>Biobank partnerships:\n<ul>\n<li>Working with a biobank to facilitate access to processed samples<\/li>\n<\/ul>\n<\/li>\n<li>Round-the-clock surveillance:\n<ul>\n<li>Ensuring unit members are available 24\/7, in required projects<\/li>\n<\/ul>\n<\/li>\n<li>Quality control:\n<ul>\n<li>Through exhaustive monitoring throughout the entirety of the processes<\/li>\n<li>In general, by accessing the operating rooms or pathology units to assess the sample as soon as possible with medical teams<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_tab][vc_tab gutter_size=\u00bb2&#8243; 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Transplantation Institute<\/title>\n<meta name=\"description\" content=\"Descubre toda la informaci\u00f3n sobre Human Biological Samples (HBS) en nuestra web. 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