{"id":5644,"date":"2023-03-02T16:06:55","date_gmt":"2023-03-02T16:06:55","guid":{"rendered":"http:\/\/dti.developallin.com\/teixits-per-a-la-investigacio\/"},"modified":"2026-04-15T10:21:09","modified_gmt":"2026-04-15T10:21:09","slug":"human-biological-samples","status":"publish","type":"page","link":"https:\/\/dtifoundation.com\/ca\/recerca-i-desenvolupament\/human-biological-samples\/","title":{"rendered":"Human Biological Samples (HBS)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;369816&#8243;][vc_column width=&#8221;2\/3&#8243;][vc_custom_heading text_color=&#8221;color-red-tpm-dti&#8221; heading_semantic=&#8221;div&#8221; text_size=&#8221;h5&#8243; text_weight=&#8221;600&#8243; uncode_shortcode_id=&#8221;210748&#8243; text_color_type=&#8221;uncode-palette&#8221;]Desenvolupament de Recerca[\/vc_custom_heading][vc_custom_heading text_color=&#8221;color-jevc&#8221; text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;459768&#8243; text_color_type=&#8221;uncode-palette&#8221;]Human Biological Samples[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;966445&#8243;]<\/p>\n<p style=\"text-align: justify;\">El departament de <strong>desenvolupament de recerca<\/strong> de la Fundaci\u00f3 DTI dona suport a grups de recerca de primer nivell per desenvolupar projectes de recerca b\u00e0sica i precl\u00ednica en l\u2019\u00e0mbit de les Ter\u00e0pies Avan\u00e7ades.<br \/>\nEls projectes impulsats per DTI se centren en desenvolupar eines humanes predictives <em>in vitro<\/em> per assolir diversos objectius:<\/p>\n<ul style=\"text-align: justify;\">\n<li><strong>Anticipar<\/strong> possibles efectes adversos, inefica\u00e7os o t\u00f2xics derivats de l\u2019acci\u00f3 de compostos immunomoduladors en pacients amb c\u00e0ncer.<\/li>\n<li><strong>Identificar<\/strong> noves dianes terap\u00e8utiques i\/o biomarcadors que puguin millorar el pron\u00f2stic dels pacients.<\/li>\n<li><strong>Dissenyar i validar<\/strong> models d\u2019organoides mitjan\u00e7ant una caracteritzaci\u00f3 exhaustiva, incloent-hi proves de f\u00e0rmacs i an\u00e0lisis \u00f2miques detallades<br \/>\n(gen\u00f2mica, transcript\u00f2mica, prote\u00f2mica i epigen\u00f2mica) tant d\u2019organoides com de teixits, per avaluar la seva similitud molecular i cel\u00b7lular amb els teixits originals.<\/li>\n<li><strong>Desenvolupar i optimitzar<\/strong> eines avan\u00e7ades per analitzar l\u2019impacte de diversos components en les estructures dels organoides, amb la finalitat d\u2019obtenir una comprensi\u00f3 m\u00e9s profunda dels seus mecanismes moleculars.<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">El desenvolupament de les ter\u00e0pies avan\u00e7ades aporta importants beneficis m\u00e8dics i socials, amb el potencial de transformar els sistemes sanitaris i millorar profundament la qualitat de vida en \u00e0mbits com:<\/p>\n<ul>\n<li style=\"text-align: justify;\"><strong>Tractament de malalties abans incurables:<\/strong> Permeten abordar afeccions rares, gen\u00e8tiques o degeneratives sense opcions terap\u00e8utiques efectives, com la distr\u00f2fia muscular, l\u2019ELA o alguns tipus de c\u00e0ncer.<\/li>\n<li style=\"text-align: justify;\"><strong>Ter\u00e0pies personalitzades:<\/strong> Ofereixen tractaments adaptats a les caracter\u00edstiques gen\u00e8tiques i biol\u00f2giques de cada pacient, millorant l\u2019efic\u00e0cia i reduint els efectes secundaris.<\/li>\n<li style=\"text-align: justify;\"><strong>Regeneraci\u00f3 i reparaci\u00f3 de teixits i \u00f2rgans:<\/strong> Poden restaurar funcions corporals deteriorades, millorant significativament la salut de pacients amb fallada org\u00e0nica o lesions.<\/li>\n<li style=\"text-align: justify;\"><strong>Reducci\u00f3 de la depend\u00e8ncia de tractaments cr\u00f2nics:<\/strong> Moltes ter\u00e0pies avan\u00e7ades ofereixen cures definitives o solucions a llarg termini, minvant la necessitat de medicaci\u00f3 constant.<\/li>\n<li style=\"text-align: justify;\"><strong>Reducci\u00f3 de l\u2019\u00fas de models animals:<\/strong> Aquestes t\u00e8cniques permeten crear models humans <em>in vitro<\/em> precisos, evitant les limitacions de la translaci\u00f3 animal-hum\u00e0 i promovent una recerca biom\u00e8dica m\u00e9s \u00e8tica i sostenible.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_tabs align=&#8221;left&#8221; el_id=&#8221;tabs-rd&#8221;][vc_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Els nostres valors&#8221; tab_id=&#8221;1683805219-1-1&#8243;][uncode_list icon=&#8221;fa fa-chevron-right2&#8243; icon_color=&#8221;color-red-tpm-dti&#8221; uncode_shortcode_id=&#8221;370697&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li><strong>Multidisciplinary<\/strong> <strong>approach<\/strong>: Coordinated teamwork with professionals from diverse fields.<\/li>\n<li><strong>Adaptability<\/strong>: Flexible methodology tailored to each project&#8217;s context and needs.<\/li>\n<li><strong>Commitment<\/strong>: Active involvement of the team throughout all phases of the process.<\/li>\n<li><strong>Availability<\/strong>: Continuous support and responsiveness to ensure project success.<\/li>\n<li><strong>Rigorous methodology:<\/strong> Strict application of protocols and quality standards at every step.<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_tab][vc_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Per qu\u00e8 DTI&#8221; tab_id=&#8221;1683805219-2-37&#8243;][vc_column_text uncode_shortcode_id=&#8221;413034&#8243;]<span lang=\"es-ES\">Per garantir que aquest proc\u00e9s essencial es realitzi amb \u00e8xit, la Fundaci\u00f3 DTI ofereix suport amb:<\/span>[\/vc_column_text][uncode_list icon=&#8221;fa fa-chevron-right2&#8243; icon_color=&#8221;color-red-tpm-dti&#8221; uncode_shortcode_id=&#8221;270589&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>Customized project design:\n<ul>\n<li>By linking biobanks, processing centers, and laboratories<\/li>\n<\/ul>\n<\/li>\n<li>Specialists obtaining fresh samples:\n<ul>\n<li>Through management of minimum cold ischemia for any type of tissue<\/li>\n<li>Shipping times of less than 24 hours in Europe<\/li>\n<\/ul>\n<\/li>\n<li>Biobank partnerships:\n<ul>\n<li>Working with a biobank to facilitate access to processed samples<\/li>\n<\/ul>\n<\/li>\n<li>Round-the-clock surveillance:\n<ul>\n<li>Ensuring unit members are available 24\/7, in required projects<\/li>\n<\/ul>\n<\/li>\n<li>Quality control:\n<ul>\n<li>Through exhaustive monitoring throughout the entirety of the processes<\/li>\n<li>In general, by accessing the operating rooms or pathology units to assess the sample as soon as possible with medical teams<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_tab][vc_tab gutter_size=&#8221;2&#8243; 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override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;369816&#8243;][vc_column width=&#8221;2\/3&#8243;][vc_custom_heading text_color=&#8221;color-red-tpm-dti&#8221; heading_semantic=&#8221;div&#8221; text_size=&#8221;h5&#8243; text_weight=&#8221;600&#8243; uncode_shortcode_id=&#8221;210748&#8243; text_color_type=&#8221;uncode-palette&#8221;]Desenvolupament de [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9289,"parent":17302,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5644","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Human Biological Samples (HBS) | DTI Foundation | Donation &amp; Transplantation Institute<\/title>\n<meta name=\"description\" content=\"Descobreix tota la informaci\u00f3 sobre Human Biological Samples (HBS) a la nostra web. 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